Human DNA polymerase forms nonproductive complexes with matched primer termini but not with mismatched primer termini
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چکیده
منابع مشابه
Human DNA polymerase kappa forms nonproductive complexes with matched primer termini but not with mismatched primer termini.
Human DNA polymerase kappa (pol kappa) is a member of the Y family of DNA polymerases that function in translesion synthesis. It synthesizes DNA with moderate fidelity and does not efficiently incorporate nucleotides opposite DNA lesions. Pol kappa has the unusual ability to efficiently extend from mismatched primer termini, and it extends readily from nucleotides inserted by other DNA polymera...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2006
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0605785103